Pumpless microfluidic devices for generating healthy and diseased endothelia
نویسندگان
چکیده
منابع مشابه
Droplet-Generating Microfluidic Devices for Soluble Assays
ogy in the pharmaceutical industry (1). Over the past decade, there has been a logarithmic increase in the industry’s ability to screen large combinatorial libraries of compounds against target molecules (2). The technology to achieve this has come in the form of robotics, high-density microplates, small volume (microliter) liquid handling, and sophisticated detection schemes. Signifi cant effo...
متن کاملMicrofluidic devices for bioapplications.
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful tool that is currently revolutionizing chemical and biological analysis by replicating laboratory bench-top technology on a miniature chip-scale device, thus allowing assays to be carried out at a fraction of the time an...
متن کاملQuantitative Biomechanics of Healthy and Diseased Human Red Blood Cells using Dielectrophoresis in a Microfluidic System.
We present an experimental method to quantitatively characterize the mechanical properties of a large number of biological cells by introducing controlled deformation through dielectrophoresis in a microfluidic device. We demonstrate the capability of this technique by determining the force versus deformation characteristics of healthy human red blood cells (RBCs) and RBCs infected in vitro wit...
متن کاملMicrofluidic Devices for Blood Fractionation
Blood, a complex biological fluid, comprises 45% cellular components suspended in protein rich plasma. These different hematologic components perform distinct functions in vivo and thus the ability to efficiently fractionate blood into its individual components has innumerable applications in both clinical diagnosis and biological research. Yet, processing blood is not trivial. In the past deca...
متن کاملMicrofluidic Devices for Insect MEMS
This work describes the development of an electroactive microwell based chemical/drug delivery system and its pupae stage implantation within Manduca Sexta moths. This forms one of the critical components in our development of Insect MEMS which aim to fuse nanodevice technology with living systems. The goal of this system is to provide “oncommand” chemically induced immobilization and subsequen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Lab on a Chip
سال: 2019
ISSN: 1473-0197,1473-0189
DOI: 10.1039/c9lc00446g